There are hundreds of different kinds of lumps, bumps and cysts associated with the skin. Fortunately, the vast majority of these are harmless and painless. The chart below provides a guide for some of the most common forms of skin lumps, bumps and cysts.
Dermatofibromas
Characteristics
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Red, brown or purple growth; generally benign
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Usually found on arms and legs
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Feels like a hard lump
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Can be itchy, tender to the touch and sometimes painful
Treatment
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Usually does not require treatment
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Most common removal by surgical excision or cryotherapy (freezing it off with liquid nitrogen)
Epidermoid Cysts (Sebaceous Cysts)
Characteristics
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Round small bumps, usually white or yellow
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Forms from blocked oil glands in the skin
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Most commonly appear on the face, back, neck, trunk and genitals
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Usually benign; occasionally leads to basal or squamous cell skin cancers
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If infected, will become red and tender
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Can produce a thick yellow, cheese-like discharge when squeezed
Treatment
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Antibiotics might be prescribed if there is an underlying infection
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Dermatologist removes the discharge and the sac (capsule) that make up the walls of the cyst to prevent recurrence
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Laser surgery may be used for sensitive areas of the skin, like the face
Folliculitis
Characteristics
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Red pimples around areas having hair
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Inflammation of the hair follicles
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Caused by infection or chemical or physical irritation (e.g., shaving, fabrics)
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Higher incidence among people with diabetes, the obese or those with compromised immune systems
Treatment
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Topical antibiotics
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Oral antibiotics
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Antifungal medications
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Eliminating the cause
Keratoacanthoma
Characteristics
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Red, dome-shaped, thick bumps with craters in the center
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Abnormal growth of hair cells
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Triggered by minor skin injury such as a cut or bug bite
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Ultraviolet radiation from sun exposure is the most common risk factor
Treatment
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Cryotherapy (freezing off the bump with liquid nitrogen
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Curettage (surgically cutting out or scraping off)
Keratosis Pilaris
Characteristics
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Small, rough white or red bumps that neither itch nor hurt
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Usually worse during winter months or when there is low humidity and the skin gets dry
Treatment
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Usually does not require treatment
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In most cases disappears on its own by age 30
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Intensive moisturizing is the first line of treatment
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For more difficult cases, use of medicated creams with urea or alpha-hydroxy acids
Lipomas
Characteristics
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Soft fatty tissue tumors or nodules below the skin’s surface
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Usually slow growing and benign
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Appear most commonly on the trunk, shoulders and neck
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May be single or multiple
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Usually painless unless putting pressure on a nerve
Treatment
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Usually does not require treatment unless it is compressing on the surrounding tissue
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Easy to remove via excision
Neurofibromas
Characteristics
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Soft fleshy growths under the skin
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Slow growing and generally benign and painless
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Pain may indicate a need for medical attention
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May experience an electrical shock at the touch
Treatment
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Usually does not require treatment, particularly if it does not cause any symptoms
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If it affects a nerve, it may be removed surgically
Skin Cysts
Characteristics
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Closed pockets of tissue that can be filled with fluid or pus
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Can appear anywhere on the skin
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Smooth to the touch; feels like a pea underneath the surface
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Slow growing and generally is painless and benign
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Only needs attention if it becomes infected or inflamed
Treatment
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Usually does not require treatment; often disappears on its own
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May need to be drained by a physician
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Inflamed cysts respond to an injection of cortisone, which causes it to shrivel

